![]() ![]() Based on in-house studies these blots detect antibodies to North American, European and Australian strains of TBRF Borrelia in patient serum samples. The TBRF ImmunoBlot is designed to detect antibodies to specific antigens of TBRF Borrelia in human serum. The ImmunoBlot has better sensitivity compared to the current Western Blot, because it t is designed to detect antibodies to major burgdorferi sensu lato specific antigens from North America and European strains as listed below:.The sensitivity of the Lyme Immunoblot is 90.9% with well-defined samples.The 31kDa Epitope confirmation test will not be required on patient samples tested by Lyme ImmunoBlots.This is higher than the traditional Western Blot. The specificity of the ImmunoBlot is 98.0% for IgM and 98.7% for IgG.burgdorferi sensu lato for clinical use with the following advantages over a Western blot: ![]() Therefore, IGeneX has developed a Lyme ImmunoBlot that is very specific and inclusive of most species of B. To develop all-inclusive Western blots would be very expensive and impractical. “These tests, when combined with Lyme IgX spot and PCR, cover the full spectrum of the disease.”Īlthough IGeneX Lyme Western blot prepared from Borrelia burgdorferi strains B31 and 297 is one of the most sensitive tests, it does not detect antibodies to all the B. Jyotsna Shah, President and CEO of IGeneX. “IGeneX’s new Lyme ImmunoBlot and the TBRF ImmunoBlot tests are the first, most inclusive and specific serologic tests for Lyme disease and TBRF,” said Dr. Thus, there is an urgent need for better diagnostic tests for Borrelisosi.īecause symptoms of Lyme and Tick-Borne Relapsing Fever are often similar, a more comprehensive battery of tests is critical for proper diagnosis. In addition, with the increase in tick populations, Borreliosis is on the rise. hermsii and a serological test that detects only B. burgdorferi (2) For TBRF Borrelia, only two serological tests, an IFA test for B. Many patients with Lyme-like symptoms are misdiagnosed because: (1) The current serological tests cannot detect antibodies to all the different strains of B. Therefore, IGeneX developed two sets of Immunoblots, Lyme ImmunoBlot IgM and IgG and TBRF ImmunoBlot IgM and IgG. However, we now know that TBRF Borrelia also causes Lyme-like symptoms. burgdorferi group was the only group that caused Lyme-like symptoms. burgdorferi group and the Tick-Borne Relapsing Fever (TBRF) Borrelia group. Lyme ImmunoBlotIgM and IgG TBRF ImmunoBlot IgM and IgG Lyme IGX Spotīorreliosis is caused by two groups of Borrelia, B. Lyme ImmunoBlotIgM and IgG TBRF ImmunoBlot IgM and IgG IGeneX Inc., a CLIA and New York-approved Reference Laboratory, specializing in testing for tick-borne diseases, is pleased to announce the launch of three new tests that are more inclusive and specific for aiding in diagnosis of Borreliosis (Lyme Disease and Tick-Borne Relapsing Fever, Borreliosis). Press release from IGeneX, October 16, 2017 ![]()
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